S3-Leitlinie zum exokrinen Pankreaskarzinom

S3 Guideline for Chronic Pancreatitis – Diagnosis, Classification and Therapy for the Radiologist S3-Leitlinie Chronische Pankreatitis: Diagnostik, Klassifikation und Therapie für die Radiologie

The prevalence and incidence of chronic pancreatitis are increasing in the Western world. The worldwide incidence is between 1.6 and 23 per 100000 with increasing prevalence [1]. Despite the fact that the disease is typically treated on an outpatient basis, over 10000 inpatient cases per year have been seen in Germany not including the over 50000 cases per year of acute episodes of chronic panc...

Text S3

We sought to characterize WPEC by quantifying per-hour log-fold change. To do so, we regressed the log gene expression on time (hour) and extracted the linear slope. For genes with monotonically increasing or decreasing expression trajectories, the utility of our WPEC measure to discriminate is obvious. Our WPEC measure can also discriminate with more complex trajectories which may be reflectiv...

S3 Table

study design, analysis and interpretation The following table summarizes several key concepts relating to sample preparation and library construction that may influence analysis and interpretation of RNA-seq data. Several initiatives are underway to develop standards and best practices that cover many of these concepts. These include: the Sequencing Quality Control (SEQC) consortium [2], the En...

S3 Text

S3 Text

We estimated clinic-averaged co-ancestries from WGS data assuming SNPs were both linked and unlinked. Linked analyses require a recombination file specifying distances between SNPs. We used a uniform recombination rate equal to 7.4 × 10−7 Morgans per base pair (Miles et al. 2016), the same as that specified in hmmIBD (Schaffner et al., n.d.). ChromoPainter essentially treats each unlinked SNP a...